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Giants vs. Angels Prediction: Road Success vs. Home Stand (April 18)

By Darin Zank
Date: 30/04/2025 9:30 pm
Location: Angel Stadium
TV: MLBTV

Betting Odds



Moneyline: SF -155/LAA +135
Total: 8

After spending most of this season on the road so far the Angels begin a two-series home-stand Friday night with the first of three games against the Giants.  
 
Lefty Tyler Anderson takes his turn on the mound for Los Angeles against Logan Webb for San Francisco.

How are we playing this game with our free baseball betting pick?

MLB Betting Odds

Friday’s baseball betting market opened San Francisco at around -145 over the Angels, with an O/U of 8. Early betting action bumped that line a dime to -155.

The Giants could also be found catching +110 on the run line.

Giants-Angels Betting Preview

San Francisco just split four games at Philadelphia, losing Thursday’s series finale 6-4. Just before that, the Giants took two of three games at the Yankees. So San Francisco is 5-3 over its last eight games.

At 13-6 overall, the Giants trail first-place San Diego by two games in the NL West.

Meanwhile Los Angeles just got swept three games at Texas, losing Thursday’s series finale 5-3. Just before that the Angels lost two of three at Houston. So Los Angeles owns a four-game losing skid heading into Friday night.

At 9-9 overall, the Angels trail the first-place Rangers by 2.5 games in the AL West.

These teams met once last year, in June when Los Angeles took two of three games at Oracle Park. Anderson picked up the W in one of those games.

Friday’s Pitching Match-Up

Anderson is 0/3 on quality starts this season, pitching on a short leash. First, he gave up three runs and two home runs in five innings at St. Louis, although Los Angeles won that game 5-4 in extra innings. Then he held Cleveland to two runs through five innings, although he also walked four, in a 6-2 Angels victory. Then last Saturday, he held Houston scoreless on one hit, although he again walked four, through 5 2/3 innings of a 4-1 LA win.

So the Angels are 3-0 with Anderson this season, and the Unders are 2-1.

In his one start against San Francisco last season, Anderson allowed just one run on five hits and five walks through 5 1/3 innings of an 8-6 Los Angeles victory.

Webb is 2/4 on quality starts this year. Two weeks ago, he held the Astros to one run through seven innings of a 3-1 Giants win and followed that up with a wonderful outing against Cincinnati, throwing seven shutout innings with zero walks and 10 strikeouts, although San Francisco lost that game 2-0. Then, last Sunday, he gave up three runs in five innings against the Yankees, walking four, but picked up the W in a 5-4 Giants victory.

So San Francisco is 3-1 with Webb, with the totals split 2-2.

In his most recent start against the Angels, back in 2023, Webb allowed one ER and seven hits through 5 2/3 innings of an 8-3 Giants win.

Splits With the Sticks

San Francisco is batting .207 against left-handed pitching this season, with a .267 team OBP and a .399 team slugging percentage. But the Giants have also scored at least five runs five times through their last eight games.

Last year we ranked the Angels among the bottom five line-ups in Baseball against right-handed pitching. This year Los Angeles is slashing .233/.297/.435 vs. righties. The Angels have also been held to 14 runs over their last six games. 

The Bullpens

The Angels bullpen owns a 5.91 ERA this season, along with a 1.67 WHIP and a 1.96 K/BB ratio.

The Giants pen owns a 1.89 ERA, a 1.01 WHIP, and a 2.71 K/BB ratio.

MLB Betting Trends

San Francisco played 19-25 against LH starters last year, and it’s 2-4 vs. lefties this season.

The Angels played 49-79 against RH starters last year, but they’re 8-8 vs. righties this year.

Totals Report

The overs are a combined 24-13 in Giants and Angels games this season.

The unders played 40-37 at Angel Stadium last season.

San Francisco at LA Angels Free Pick

We give San Francisco our baseball handicapping check-marks in the pitching match-up, in the bullpen comparison and with the sticks. So we like the Giants. We also like taking chances. So in knowing San Francisco will bat nine times we’ll give the run and a half and play the Giants against the run line.

Free Pick: Take the Giants -1.5
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