Matt Chapman San Francisco Giants

Brewers vs Giants Betting Preview | April 21, 2025

By Darin Zank
Date: 21/04/2025 9:45 pm
Location: Oracle Park
TV: MLBN

Betting Odds



Moneyline: SF -140/Mil +120
Total: 8

National League playoff hopefuls meet when the Giants and Brewers open a three-game series out by McCovey Cove Monday night.

Lefty Robbie Ray, 3-0 on the season, gets the call for San Francisco here against newly acquired rookie righty Quinn Priester for Milwaukee.

How are we playing this game with our free baseball betting pick?

MLB Betting Odds

Monday’s baseball betting market opened San Francisco at around -145 over Milwaukee, with an O/U of 8. Early betting action dipped that line to -140.

Brewers-Giants Betting Preview

Milwaukee just took two of three games at home from the Athletics over the weekend, winning Sunday’s series rubber match 14-1.

Earlier last week, the Brewers took two of three games from Detroit. So Milwaukee is 4-1 over its last five games.

At 12-10 overall, the Brewers trail the first-place Cubs by one game in the NL Central.

Meanwhile, San Francisco just dropped two of three games at the Angels over the weekend, losing Sunday’s series rubber match 5-4 when Los Angeles scored four runs in the bottom of the ninth.

Earlier last week, the Giants split four games at Philadelphia, and just before that, they took two of three games at the Yankees. So San Francisco finished that road trip 5-5.

At 14-8 overall, the Giants trail first-place San Diego by two games in the NL West.

Last year, Milwaukee took the season series from San Francisco four games to two.

Monday’s Pitching Match-Up

Ray is 1/4 on quality starts this season. Last Wednesday he allowed four runs on six hits and five walks through just four innings against the Phillies, although San Francisco won that game 11-4. And over his last three starts he’s allowed six runs and 12 hits through 14 innings, although he also walked 14 over that span.

The Giants are 4-0 with Ray this season, the overs 3-1.

This will be Ray’s first start against Milwaukee since 2019, and that’s a long time ago.

Priester is 0/2 on quality starts this year, but that’s only because he’s been pitching on a short leash. First, he held Colorado to one run through five innings, although the Brewers lost that game 7-2. Then last Tuesday he held Detroit scoreless on one hit through five frames of a 5-0 Milwaukee victory.

So the Brewers are 1-1 with Priester, the unders 2-0.

In his one career start against San Francisco, for Pittsburgh in August of last season, Priester tossed six innings of three-hit, shutout ball. The Pirates lost that game 4-0.

Splits With the Sticks

Milwaukee is batting .235 against left-handed pitching this season, with a .303 team OBP and a .329 team slugging percentage.

San Francisco is slashing .232/.320/.407 against right-handed pitching.

The Bullpens

The Giants bullpen owns a 2.22 ERA this season, along with a 1.03 WHIP and a 2.65 K/BB ratio.

The Brewers pen owns a 5.14 ERA, a 1.36 WHIP, and a 2.28 K/BB ratio.

MLB Betting Trends

Milwaukee played 24-24 last year against LH starters and it’s 5-4 vs. lefties this season.

San Francisco played 61-57 against RH starters last year, and it’s 12-2 vs. righties this year.

Totals Report

The Under is 12-8 in Brewers games this season.

The overs are 15-7 in Giants games.

The Under was 3-2-1 in Brewers-Giants games last year.

Prop Board

Milwaukee OF Chourio, who’s slugging .521 this season, is catching +140 to bat over 1.5 total bases.

Free MLB Pick

Ray gets the check-mark in the pitching match-up but he’s been kinda wild this season so it’s close. From there we also give San Francisco edges with the sticks and in the bullpen comparison. Also, the Giants are already 12-2 against RH starters this season. We’re betting on San Francisco Monday night.

Free Pick: Take the Giants -140
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